
When Amy Neary, CEO, launched Prime IV Hydration & Wellness in 2017, she set out to reimagine the way people take care of their health and futures. What began as a self-funded vision to make nutrient therapy more accessible has grown into one of the fastest-growing franchises in the wellness space. Today, the brand has over 175 locations open, over 300 units sold and new services on the horizon. By Shelby Green
ENTREPRENEUR
When Amy Neary, CEO, launched Prime IV Hydration & Wellness in 2017, she set out to reimagine the way people take care of their health and futures. What began as a self-funded vision to make nutrient therapy more accessible has grown into one of the fastest-growing franchises in the wellness space. Today, the brand has over 175 locations open, over 300 units sold and new services on the horizon.
Prime IV Hydration & Wellness offers a wide range of services, including vitamin-infused hydration, massage chairs, blankets and personalized consultations. The company is committed to delivering personalized, science-backed wellness care in a setting that feels luxurious and empowering. Every detail of the business is designed to elevate wellness and the client experience.
“Our premium, proactive approach has truly tapped into a powerful trend,” said Neary. “Consumers today are actively investing in their health rather than just reacting to illness, and we’re here to meet that demand.”
Through this mission, Prime IV Hydration & Wellness has seen record-breaking success. In 2024, the brand opened 55 new locations and earned 13 major national awards. Neary was even recognized as one of Franchise Dictionary Magazine’s 50 Women of Wonder, and the brand was celebrated for its culture, innovation and performance. In 2025, the brand is ready to reach new heights by doubling its business success team and increasing resources for training, profitability coaching and operational excellence.
Prime IV Hydration & Wellness’s lean operational model and low overhead requirements make it an attainable, profitable business opportunity for franchisees eager to be part of something meaningful. Many owners manage a spa with as few as two medical professionals, allowing for lean operations and a robust membership model that drives recurring revenue.
“We’ve built Prime IV to empower business owners,” said Neary. “When our franchisees succeed, their communities thrive. That’s what drives us.”
For those looking for a brand that combines affordability, lean operations, recurring revenue and a profound purpose, Prime IV Hydration & Wellness is an undeniable choice. With a growing national footprint, strategic infrastructure investments and a culture that values its franchise partners like family, it’s no wonder so many are joining the movement.
Shelby Green